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A profile is a set of "adjustments" applied to a given template just prior to printing which compensates for anomalies unique and peculiar to a given printer (to which the profile is assigned). This means if you set a template up and then print a sample set of data and find that the items are not all aligned the same on each label, you need to set up a profile for each printer to make up for the differences in printing styles, such as the shifting of text to the left, right, top or bottom.
If your labels are printing just the way you want, you will not need a profile.
To add a new profile, you want to click on the 'Profiles' button at the top of your page and choose 'New Profile'
Using the form that appears you can create a profile to fix any problems with your template.
After saving, your profiles will appear on the 'Manage Profiles' page.
Once you have saved your new profile, you can return to the list of templates and choose to edit the template that this profile is for.
See the full documentation for Label Profiles in the manual (online).
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